Carbomers are polymerized form of acrylic acid monomers. It is widely used in pharmaceutical industry. Polymers has typical properties such as acidity/alkalinity, density, dissociation constant, glass transition temperature, melting point, particle size, moisture content, solubility and viscosity. Carbomers are dispersed in either aqueous or alcoholic solution to form uniform dispersion under stirring. Carbomers need to be neutralizing with alkali to form cross linking between polymers. Swelling of polymers takes place during neutralization. Neutralization increases viscosity of carbomer solution. Carbomers are sold in market with different brand name. Carbomer has applications in solid, liquid and semi-solid dosage forms. Carbomers are available in different grades with different combination with other polymers. Carbomers are used as gelling agents or viscosity modifier in semisolid dosage form or liquid dosage forms. pH of carbomer plays an important role in building viscosity by altering the crosslinking.
Loading....